Research - Cystic Fibrosis

Poor nutritional status is associated with declining lung function in patients with cystic fibrosis (CF). Phase angle (PhA), is a direct measure of the integrity of the cellular membrane and has been shown to be an important biomarker of cellular health and nutritional status in numerous clinical diseases. Furthermore, PhA reference values for a healthy population, stratified by body mass index (BMI), gender and age, exist, providing a prognostic potential.

Skeletal muscle weakness is an important complication of chronic respiratory disease. The effect of acute exacerbations on strength in patients with cystic fibrosis is not known.